Researchers find ways to treat post-traumatic stress disorder

By Admin
The researchers at the Western University have found a way of treating both post-traumatic stress disorder and drug addiction by selectively blocking t...

The researchers at the Western University have found a way of treating both post-traumatic stress disorder and drug addiction by selectively blocking the patient’s recall of memories.

The research study sheds light on how a mechanism in the brain’s pre-limbic cortex regulates the recall of both negative experiences and those associated with PTSD, as well as the positive memories that drug addicts associate with being high.

The Lauzon’s team also believed that they have found a way to suppress the spontaneous recall of both the pleasurable and traumatic memories without permanently changing the memories themselves. 

Laviolette, an associate professor in the Departments of Anatomy and Cell Biology, and Psychiatry said, “These findings are very important in disorders like PTSD or drug addiction. One of the common problems associated with these disorders is the obtrusive recall of memories that are associated with the fearful, emotional experiences in PTSD patients. And people suffering with addiction are often exposed to environmental cues that remind them of the rewarding effects of the drug.”

Mr. Laviolette also said, “This can lead to drug relapse, one of the major problems with persistent addictions to drugs such as opiates. So what we’ve found is a common mechanism in the brain that can control recall of both aversive memories and memories associated with rewarding experience in the case of drug addiction.” 

The researchers used lab rats and found that by stimulating a sub-type of dopamine receptor in the brain known as the D1 receptor, they were able to completely block the recall of both traumatic and reward-related memories.

The researchers believe that if they can learn to block the recall of these memories in humans as well, then they may have a biochemical target for which to create new memory-blocking pharmaceuticals to treat PTSD and drug addiction.

The researchers believe that their research could potentially lead to less invasive ways to curb the recall of unwanted memories.  Researchers also said, “The interesting thing about our findings is that we were able to prevent the spontaneous recall of these memories, but the memories were still intact. We were not inducing any form of brain damage or actually affecting the integrity of the original memories.” 


Featured Articles

Johnson & Johnson: Turning supplier spend into local support

Johnson & Johnson’s Global Supplier Diversity & Inclusion team is growing spending with social enterprises around the globe to expand its impact

Seasonal Affective Disorder’s impact on health & solutions

Dr Ravi Gill & Dr. Naomi Newman-Beinart discuss Seasonal Affective Disorder and its treatments, from vitamin D spray to light therapy

CGI teams up with Totalmobile for digital healthcare service

CGI is driving efficiency in healthcare. Hear from Helena Jochberger, at Manufacturing Digital LIVE, a free virtual event on Wednesday 6th December 2023

Deloitte: generative AI can improve access to healthcare

Technology & AI

Wipro & NVIDIA’s revolutionary healthcare uses generative AI


Healthtech platform CoverSelf extends seed round to US$8.2m

Technology & AI