Canadian researchers find protein that can raise production of low density lipoprotein cholesterol

By Admin
A team of Canadian researchers have found a protein that can increase the production of low density lipoprotein cholesterol. The scientists said the re...

A team of Canadian researchers have found a protein that can increase the production of low density lipoprotein cholesterol.

The scientists said the resistin which is secreted by fatty tissue, causes human liver cells to produce more LDL, known as the bad form of cholesterol that can increase the risk of cardiovascular diseases.

According to the Heart and Stroke Foundation of Canada, the resistin also degrades LDL receptors in the liver that makes it harder for the organ to remove from a person’s body, and can accelerate the accumulation of cholesterol in the arteries. 

The researchers also said, “The research also shows that resistin adversely impacts the effects of statins, the main cholesterol-reducing drug used in the treatment and prevention of cardiovascular disease.”

According to Dr. Shriya Rashid, 40% of all the people who take statins are actually resistant to their affects, and high levels of resistin in the blood could be to blame for their inability to lower their cholesterol.

Dr. Shriya also said, the findings could lead to new medicines that help resistin and inhibit its production, thus restoring the effectiveness of statins. Heart and Stroke Foundation spokesperson Dr. Beth Abramson said, “The possibilities for improved therapy for the causes of cardiovascular diseases are very important.” He also said, “About 40% of Canadians have high blood cholesterol levels and it’s a significant health concern in Canada.”

The findings also demonstrate how important it is for a person to keep their cholesterol and weight down, as both high LDL levels and obesity are contributing factors in heart disease and stroke.

Share
Share

Featured Articles

TrueBinding’s antibody drugs fight Alzheimer’s Disease

Dongxu Sun, CEO at TrueBinding, shares how its research & antibody drug development is fighting illnesses such as Alzheimer’s Disease, stroke & more

Cardinal Health’s clinically integrated pharma supply chain

Peter Siavelis, SVP & General Manager, Health System and Provider Distribution & Services at Cardinal Health, discusses the integrated pharma supply chain

Healthcare Digital news roundup: digital healthcare & AI

This week in Healthcare Digital, we looked at digital skills for healthcare leaders, medical technology & acoustic AI used in digital cough monitoring

Hospitals must embrace IoMT device security

Hospitals

Mental health support for working women and mothers

Digital Healthcare

Digital evolution delivers better healthcare outcomes

Digital Healthcare