Orlistat under review after links to liver problems

By Admin
Weight loss drug orlistat has come under review by the European Medicines Agency (EMA) after four recent cases of serious liver toxicity were linked to...

Weight loss drug orlistat has come under review by the European Medicines Agency (EMA) after four recent cases of serious liver toxicity were linked to the drug, including one fatal case.

Medicines containing the drug, which has been available since 1998, may have their licenses changed or revoked following the review.

Orlistat was the most commonly prescribed weight loss drug in England in 2009. Since then, other weight loss drugs have been suspended from sale, meaning orlistat has become even more widely prescribed. An estimated 38 million people worldwide have used the drug.

To read the latest edition of Healthcare Global, click here

Orlistat is found in the prescription-only Xenical, as well as over-the-counter medicine, Alli.

In a statement about the review, the EMA commented: “The Committee is now reviewing all relevant data on the risk of hepatotoxicity of orlistat-containing medicines and will issue an opinion on whether or not the marketing authorisations for these medicines should be revoked, suspended or changed.”

Links between orlistat and liver damage have been made in the past, but reports have sometimes been inconclusive. The EMA noted that the number of suspected cases is small compared to the number of people that have used the drug.

Share

Featured Articles

Wolters Kluwer Health: health equity and telehealth

Greg Samios, President & CEO at Wolters Kluwer Health Clinical Effectiveness, explores the role of health equity and telehealth in post-pandemic healthcare

World Mental Health Day: how parents can help stop bullying

How can parents help a child that is being bullied - or is a bully? Ready for World Mental Health Day, Dr. Monica Vermani explains what can be done

The Taiwan Excellence Award Winners on new technologies

Cypress Technology, Dacian Technology Material, Chroma ATE, Taiwan Advanced Nanotech & iDRC Chyng Hong Electronics are the Taiwan Excellence Award Winners

World Hepatitis Summit 2022 to support healthcare workers

Hospitals

5 minutes with Yoni Nevo, CEO of Sweetch

Technology & AI

Canada’s telehealth support for Ukrainian healthcare workers

Technology & AI